2019年发表文章

1. Long JH#, Hu ZQ#, Xue H, Wang Y, Chen J, Zhou J, Liu LN, Qiu W, Zhang SC, Ouyang Y, Ye YN, Xu GQ, Long L, Zeng Z*. Vascular endothelial growth factor (VEGF) impairs the motility and immune function of human mature dendritic cells through the VEGF receptor 2‐RhoA‐cofilin1 pathway. Cancer Sci. 2019;110(8):2357-2367.

2. Zhang SC, Zhang E, Long JH, Hu ZQ, Peng J, Liu LN, Tang FZ, Li L, Ouyang Y*, Zeng Z*. Immune Infiltration in Renal Cell Carcinoma. Cancer Sci. 2019;110(5):1564-1572.

3. Cui GZ, Wang ZJ, Hong W, Liu YJ, Chen ZH, Cui Q*, Song XJ*. Enhancing tricarboxylate transportation-related NADPH generation to improve biodiesel production by Aurantiochytrium. Algal Research. 2019;40: 101505.

4. Huang WZ#, Hu WH#, Wang Y, Chen J, Hu ZQ, Zhou J, Liu LN, Qiu W, Zhang SC, Ouyang Y, Ye YN, Long JH, Zeng Z*. A mathematical modelling of initiation of dendritic cells induced T cell immune response. Int J Biol Sci. 2019;15(7):1396-1403.

5. Sheng-Fa Su#, Mei Li#, Yi-Chao Geng#, Wen-Gang Yang, Zhu Ma, Qing-Song Li, Yin-Xiang Hu, Wei-Wei Ou Yang, Ling-Feng Liu, Bing Lu*. Randomized phase II study of pemetrexed-cisplatin or docetaxel-cisplatin plus thoracic intensity-modulated radiation therapy in patients with stage IV lung adenocarcinoma. Am J Cancer Res. 2019; 9(6): 1235-1245.

6. Yang J, Song H, Cao K, Song JL, Zhou JJ*. Comprehensive analysis of Helicobacter pylori infection-associated diseases based on miRNA-mRNA interaction network. Brief Bioinform.2019;20(4): 1492–1501.

7. Cao K, Xiang J, Dong YT, Xu Y, Li Y, Song H, Zeng XX, Ran LY, Hong W, Guan ZZ*. Exposure to fluoride aggravates the impairment in learning and memory and neuropathological lesions in mice carrying the APP/PS1 double-transgenic mutation. Alzheimers Res Ther. 2019;11(1): 35. doi: 10.1186/s13195-019-0490-3.

8. Yuan-Yong Yang#,*, Guo Yang#, Cheng Cheng, Ying-Xian Li, Ji-Quan Zhang, Wei Feng, Yong-Long Zhao, Lei Tang*. Catalyst-free Cleavage of Amide and C-O Double Bond for the Diastereoselective Synthesis of Trifluoromethyl-Containing Dihydrooxazole Derivatives. Org Lett. 2019;21(7):2236-2240.

9. Cheng Cheng，Ying-Xian Li, Ji-Quan Zhang, Yong-Long Zhao，Lin Zhang，Chun Li，Yu-she Yang，Lei Tang*, Yuan-Yong Yang*. Organo-Catalyzed Asymmetric Amination of 4-Arylisoquinoline-1,3(2H,4H)-dione Derivatives in the Construction of Quaternary Stereocenters. Advanced Synthesis & Catalysis.2019;361(23):5317-5321.

10. Huanxian Chang, Tingting Di, Ya Wang, Xianying Zeng, Guoxi Li, Qi Wan, Wenfeng Yu*, Ling Chen*. Seipin deletion in mice enhances phosphorylation and aggregation of tau protein through reduced neuronal PPARγ and insulin resistance. Neurobiol Dis. 2019;127: 350-361. doi: 10.1016/j.nbd.2019.03.023.

11. Ying Xiao#, Xiaohan Jiang#, Can Peng#, Yingying Zhang, Yawen Xiao, Dan Liang, Mingjun Shi, Yuanyuan Wang, Fan Zhang, Bing Guo*. BMP-7/Smads-induced inhibitor of differentiation 2 (Id2) upregulation and Id2/Twist interaction was involved in attenuating diabetic renal tubulointerstitial fibrosis. Int J Biochem Cell Biol. 2019;116:105613.

12. Lingling Liu#, Yuanyuan Wang#, Rui Yan, Luqun Liang, Xingcheng Zhou, Huiming Liu, Xiaohuan Zhang, Yanwen Mao, Wei Peng, Ying Xiao, Fan Zhang, Lirong Liu, Mingjun Shi*, Bing Guo*. BMP-7 inhibits renalfibrosis in diabetic nephropathy via miR-21 downregulation. Life Sci. 2019;238:116957.

13. Yuanyuan Wang#, Yanwen Mao#, Xiaohuan Zhang, Huiming Liu, Wei Peng, Luqun Liang, Mingjun Shi, Ying Xiao, Yingying Zhang, Fan Zhang, Rui Yan*, Bing Guo*. TAK1 may promote the development of diabetic nephropathy by reducing the stability of SnoN protein. Life Sci. 2019;228:1-10.

14. Yang J, Zhang YQ, Song H*. A disparate role of RP11-424C20.2/UHRF1 axis through control of tumor immune escape in liver hepatocellular carcinoma and thymoma. Aging (Albany NY). 2019;11(16): 6422-6439.

15. Rui Yan, Yuanyuan Wang, Mingjun Shi, Ying Xiao, Lirong Liu, Lingling Liu, Bing Guo*. Regulation of PTEN/AKT/FAK pathways by PPARγ impacts on fibrosis in diabetic nephropathy. J Cell Biochem. 2019. doi: 10.1002/jcb.27937.

16. Xiaoting Xu, Tingwen Lei, Wenchao Li, Hailong Ou*. Enhanced cellular cholesterol efflux by naringenin is mediated through inhibiting endoplasmic reticulum stress-ATF6 activity in macrophages. Biochim Biophys Acta Mol Cell Biol Lipids. 2019;1864(10):1472-1482.

17. Yuanyong Yang#,*, Yingxian Li#, Cheng Cheng, Guo Yang, Shuiying Wan, Jiquan Zhang, Yuanhu Mao, Yonglong Zhao, Lin Zhang, Chun Li, Lei Tang*. Reductant-Free Aerobic Hydroxylation of Isoquinoline-1,3(2H,4H) dione Derivatives. J Org Chem. 2019;84(4):2316-2324.

18. Yuanyuan Wang#, Lingling Liu#, Wei Peng, Huiming Liu, Luqun Liang, Xiaohuan Zhang, Yanwen Mao, Xingcheng Zhou, Mingjun Shi, Ying Xiao, Fan Zhang, Yingying Zhang, Lirong Liu, Rui Yan, Bing Guo*. Ski-related novel protein suppresses the development of diabetic nephropathy by modulating ransforming growth factor-β signaling and microRNA-21 expression. J Cell Physiol. 2019;234(10):17925-17936.

19. Jiang YH#,*, Wang JX#, Yang B, Wang QR, Zhou JJ, Yu WF. Molecular characterization of a debilitation-associated partitivirus infecting the pathogenic fungus Aspergillus flavus . Front Microbiol. 2019;10:626.

20. Zhang SC#, Hu ZQ#, Long JH, Zhu GM, Wang Y, Jia Y, Zhou J, Ouyang Y*, Zeng Z*. Clinical Implications of Tumor-Infiltrating Immune Cells in Breast Cancer. J Cancer. 2019;10(24):6175-6184.

21. Huang Z#, Zhao X#, Wu X, Xiang L, Yuan Y, Zhou S*, Yu W*. LncRNA UCA1 facilitated cell growth and invasion through the miR-206/CLOCK axis in glioma. Cancer Cell Int. 2019;19:316.

22. Song H#, Yang J#, Zhang YQ, Zhou JJ*, Li YM*, Hao XJ*. Integrated analysis of pseudogene RP11-564D11.3 expression and its potential roles in hepatocellular carcinoma. Epigenomics. 2019;11(3):267-280.

23. Yang J#, Song H#, Chen L, Cao K, Zhang YQ, Li YM*, Hao XJ*. Integrated analysis of microfibrillar-associated proteins reveals MFAP4 as a novel biomarker in human cancers. Epigenomics. 2019;11(1):1635-1651.

24. Yang J, Song H*. Identification of long noncoding RNA RP11-169F17.1 and RP11-669N7.2 as novel prognostic biomarkers of stomach adenocarcinoma based on integrated bioinformatics analysis. Epigenomics. 2019;11(11):1307-1321.

25. Duan JJ, Zhang QF*, Hu XH, Lu DQ, Yu WF*, Bai H*. N4-acetylcytidine is required for sustained NLRP3 inflammasome activation via HMGB1 pathway in microglia. Cell Signal. 2019;58:44-52.

26. Gao R, Wu XW, Huang Z, Wang B, Li FH, Xu H*, Ran L*. Anti-tumor effect of aloe-emodin on cervical cancer cells was associated with human papillomavirus E6/E7 and glucose metabolism. Onco Targets Ther. 2019;12:3713-3721.

27. Huang XL, Huang LY, Cheng YT, Li F, Zhou Q, Wu C, Shi QH, Guan ZZ, Liao J*, Hong W*. Zoledronic acid inhibits osteoclast differentiation and function through the regulation of NF-κB and JNK signalling pathways. Int J Mol Med. 2019;44: 582-592.

28. Zhao L, de Hoog S, Hagen F, Kang Y, Al-Hatmi AMS*. Species borderlines in Fusarium exemplified by F. circinatum/F. subglutinans. Fungal Genet Biol. 2019;132:103262.

29. Li FH#, Xiang L#, Ran L, Zhou S, Huang Z, Chen M*, Yu W*. BNIP1 inhibits cell proliferation, migration and invasion, and promotes apoptosis by mTOR in cervical cancer cells. Eur Rev Med Pharmacol Sci. 2019;23(4): 1397-1407.

30. Jian-Ta Wang#，Jin-Gang Peng，Ji-Quan Zhang，Zhong-Xiao Wang，Yi Zhang，Xun-Rong Zhou，Jing Miao，Lei Tang*. Novel berberine-based derivatives with potent hypoglycemic activity. Bioorg Med Chem Lett. 2019;29(23):126709.

31. Li XY*, Xiao B*, Guo Y*, Xiao Y*, Xiao S*. Cucurbit[7]uril enhances photosensitization of porphyrins in Neuroblastoma cells. Photodiagnosis Photodyn Ther. 2019;25:364-368.

32. Changcheng Guo#, Fang Liu#, Li Zhu#, Fangcao Wu, Guzhen Cui, Yan Xiong, Qiong Wang, Lin Yin, Caixia Wang, Huan Wang, Xiaojuan Wu, Zhengrong Zhang, Zhenghong Chen*. Analysis of culturable microbiota present in the stomach of children with gastric symptoms. Braz J Microbiol. 2019;50(1):107-115.

33. ShengFa Su, LingFeng Liu, YiChao Geng, WeiWei OuYang, Zhu Ma, QingSong Li, ChaoFen Zhao, Mei Li, Yu Wang, DaXian Luo, WenGang Yang, ZhiXu He, Bing Lu*. Pemetrexed plus cisplatin versus docetaxel plus cisplatin for stage IV lung adenocarcinoma based on propensity score matching. Anti-Cancer Drugs. 2019; 30: 295-301.

34. Wang D, Huang Z, Li L, Yuan Y, Xiang L, Wu X, Ni C*, Yu W*. Intracarotid cold saline infusion contributes to neuroprotection in MCAO‑induced ischemic stroke in rats via serum and glucocorticoid‑regulated kinase 1. Mol Med Rep. 2019;20(4): 3942-3950.

35. Jie Xiang, Kun Cao, Yang-Ting Dong, Yi Xu, Yi Li, Hui Song, Xiao-Xiao Zeng, Long-Yan Ran, Wei Hong, Zhi-Zhong Guan*. Lithium chloride reduced the level of oxidative stress in brains and serums of APP/PS1 double transgenic mice via the regulation of GSK3β/Nrf2/HO-1 pathway. Int J Neurosci. 2020;130(6):564-573.

36. HaoChen#, LinZheng#, Chao-YeMei, Zi-PengGong ,Yong-JunLi, Si-YingChen, Yan-Yu Lan, Yong-Lin Wang, Ai-Min Wang, Yue-Ting Li, Yong Huang*. Simultaneous Determination of Three Bioactive Constituents fromBletilla striataby UPLC-MS/MS and Application of the Technique to Pharmacokinetic Analyses. Evid Based Complement Alternat Med. 2019;2019:8942512.

37. Lin Zheng#, Yueting Li#, Zuying Zhou , Wenying Xiang , Zipeng Gong, Siying Chen, Yonglin Wang, Aimin Wang, Yanyu Lan, Yongjun Li*,Yong Huang*. Comparative pharmacokinetics of quercitrin, astragalin, afzelin, and taxifolin in plasma after oral administration of Polygonum orientaleinflorescence in sham-operated and myocardial ischemia-reperfusion injury rats. Xenobiotica. 2020;50(7):822-830.

38. Wang LX, Cao Y*, Guan ZZ, Luo GH, Luo L, Yang XS, Chu ML. Prostatic epithelial cells and their high expressions of CKIP-1 affect the TGF-β1expression levels which might reduce the scar formation in remodeling stage at prostatic urethral wounds after wound repair. Int Urol Nephrol. 2020;52(1):97-106.

39. Chang Yang, Tao Xia, Changquan Wang, Huiyuan Sun, Yongjun Li, Zipeng Gong, Yueting Li, Lin Zheng*, Yong Huang*. Using the UPLC-ESI-Q-TOF-MSE method and intestinal bacteria for metabolite identification in the nonpolysaccharide fraction from Bletilla striata. Biomed Chromatogr. 2019;33(11):e4637.

40. Lingling Fan, Bilan Luo, Zhongfu Luo, Li Zhang, Judi Fan, Wei Xue, Lei Tang*,Yong Li*. Synthesis and antifungal activities of 3-substituted phthalide derivatives. Zeitschrift für Naturforschung B. 2019;74(11-12): 811-818.

41. Lou DD#, Zheng D#, Ma RR, Zhang KL, Pan JG, Liu YJ, Yu YN, Guan ZZ*. Altered fission 1 and mitofusin1 in mitochondria induced by exposure to fluoride caused apoptosis in SH-SY5Y cells. Fluoride. 2019;52(2): 116-134.

42. Deng J, Zeng XX, Liu XH, Chen D, Dong YT, Song H, Li Y, Guan ZZ*. Screening and verification of differential DNA methylation genes in the peripheral blood cells of children with skeletal fluorosis in Guizhou province of China. Fluoride. 2019;52(2):135-148.

43. Zeng XX, Deng J, Xiang J, Dong YT, Cao K, Liu XH, Chen D, Ran LY, Yang Y, Guan ZZ*. Resveratrol attenuated the increased level of Oxidative stress in the brains and the deficit of learning and memory of rets with chronic fluorosis. Fluoride. 2019;52(2):149-160.

44. Struneck, Anna#,*, Struneck, Otakar;Zhi Zhong Guan. The resemblance of fluorosis pathology to that of autism spectrum disorder: A mini-review. Fluoride.2019;52 (2):105-115.

45. Hong Wei#,*, Yang Jing#, Cheng Yumei, Huang Xiaolin, Rao Fengqin, Zhang Ting, Wang Pixiang, Liao Jian, Qi Xiaolan, Guan Zhizhong, Chen Zhenhong, Cui Guzhen. Bacteria co-colonizing with Clostridioides difficile in two asymptomatic patients. Open Life Sciences. 2019,14(1):628-637.

46. Jiamou Ren，Xiaoling Wang, Yumei Gao, Fan Wang, Zhizhong Guan, Xiaolan Qi*. The expression of the nicotinic acetylcholine receptor α3 subunit in the brains of patients with Alzheimer’s disease and its effects on α- and γ-secretases and Notch signal transduction in SH-SY5Y cells. Int J Clin Exp Pathol 2019;12(9):3644-3652.

47.黄晓林，廖健*，洪伟，李芳，程余婷，周倩，董强.破骨细胞形成过程中唑来膦酸的作用途径及机制.中国组织工程研究, 2019, 23(17): 2716-2721.

48.袁桃花，黄瑜键，李佳豪，曹恒，吴昌学*，吴宁* .贵州苗药方“四大血”对CIA大鼠滑膜血管增生的作用机制.西安交通大学学报(医学版), 2019, 40(5): 824-829.

49.陈相好，刘芳，王彩霞，陈峥宏，洪伟，蔡梦迪，张峥嵘，綦廷娜，廖永慧，谷俊莹*，崔古贞* .高效严谨型大肠杆菌Targetron基因打靶系统的构.生物技术通报, 2019, 35(6): 213-220.

50.段娟娟，张启芳*，黄宗华，曾红梅，柏华*.组织蛋白酶B通过瞬时受体电位黏蛋白- 1对核苷酸结合寡聚化结构域样受体蛋白3炎症小体活化的影响.中国医学科学院学报, 2019, 41(2): 208-215.

51.王纯，王胜远，刘明海，何琪，钟毅，梁璐璐，何冬玲，官志忠，刘艳洁* .慢性氟中毒大鼠脑组织Erk激酶、AMPA受体亚基GluR1和GluR2的表达及硫酸软骨素的保护作用.中华地方病学杂志, 2019, 38(6): 446-452.

52.吕园园，王晓玲，邓于新，李毅，官志忠，齐晓岚*. α3神经型尼古丁受体基因下调对SH-SY5Y DYN1和AP180表达的影响.中国老年学杂志, 2019, 39(9): 2225-2227.

53.牟登峰，郑丹，王琪，黄仕美，官志忠，于燕妮，楼迪栋* .甲基苯丙胺对体外培养SH-SY5Y细胞线粒体膜电位、超微结构及Mfn1、Fis1蛋白表达的影响.中国药理学通报, 2019, 35(7)：935-939.

54.董智慧，吕菊，任真奎，官志忠，禹文峰.激活原代星形胶质细胞α7尼古丁胆碱能受体对PI3K/Akt/HSP70信号通路的影响.中国老年学杂志，2019,39(22):5577-5581.

55.任真奎，董智慧，吕菊，谢鹏，胡玉梅，官志忠，禹文峰. PNU282987通过α7神经型尼古丁受体激活PI3K/Akt/HSF1信号通路上调星形胶质细胞内源性αB-crystallin抑制Aβ聚集的研究.中国药理学与毒理学杂志，2019,33(06):475-476.

56.尹丹，曹颖*，王礼鑫，马亮，褚明亮，王剑，文建力，官志忠.肠型胃癌细胞中酪蛋白激酶2相互作用蛋白1与转化生长因子β1表达的相关性.实用医学杂志, 2019, 35(2): 276-280.

57.骆梅，周建奖，王琴容，杨丽萍，陈学书，龙妮娅，谢渊，赵艳. DKK1对胃癌AGS细胞生长、周期和凋亡的影响.中国肿瘤生物治疗杂志，2019,26(12):1324-1330.

58.鲍丽雅，黄婷婷，赵艳，李超，陈定宇，王琴容，周建奖，谢渊.幽门螺杆菌毒力蛋白CagA对胃癌细胞线粒体自噬相关蛋白表达的影响.中国病原生物学杂志，2019，14（12）：1394-1397

59.杨丽萍，贾岑岑，龙妮娅，骆梅，杨丹，王珺，谢渊，赵艳，王琴容，周建奖* . 腺病毒载体介导CagA基因表达对原代胃癌细胞糖酵解代谢酶表达的影响.中国病原生物学志,2019,14(11):1297-1302+1311.

60.宋菲#，杨健，王春，王霞，李维维，潘洁，兰燕宇*，刘亭*. Cocktail探针药物法评价羊耳菊对大鼠CYP450酶活性的影响.中国实验方剂学杂志,2019,25(2):60-67.

61.郑林#，陈浩，孙慧园，杨武，李勇军，巩仔鹏，李月婷，黄勇*.头花蓼提取物在肾盂肾炎模型与正常大鼠体内的组织分布比较研究.中国新药杂志,2019(8):1008-1016.

62.陈浩#，王昌权，夏涛，李月婷，王永林，黄勇，李勇军，郑林*.基于大鼠在体肠灌流模型研究白及有效部位在肠道的可吸收及代谢成分.天然产物研究与开发,2019,31(5):772-778.

63.覃小丽，陈浩，夏涛，黄勇，巩仔鹏，李月婷，李勇军，郑林*.基于UPLC-Q-TOF-MS技术的黑骨藤血清药物化学分析.中国实验方剂学杂志,2019,(6):125-129.

64.刘春花，陆定艳，游景瑞，王爱民，兰燕宇，王永林，刘亭*.薯莨抗H2O2诱导的H9c2细胞氧化损伤作用的有效部位筛选研究.中药材,2019(11):2678-2682.

65.陆定艳，李靖，孙佳，薛维娜，何彬，李勇军，王永林，林昌虎*，刘亭*.参芎葡萄糖注射液通过激活PI3K/AKT通路拮抗H2O2诱导H9c2细胞凋亡.中国中药杂志,2019,44(17):3773-3779.

66.刘香香，李靖，张煜彬，彭高发，兰燕宇，李勇军，王永林，杨畅，刘亭*. PCR法快速鉴别川贝母真伪.药物分析杂志,2019,39(10):1844-1851.

67.毛彦稳，张小欢，刘慧铭，王圆圆，汤磊，郭兵⁎.硫辛酰胺对高糖条件下肾小管上皮细胞氧化应激及转化生长因子β激活酶1和核转录共抑制因子蛋白表达的影响.实用医学杂志, 2019, 35(19):2993-2997+3003.

68.刘慧铭，刘玲伶，周星丞，彭伟，张小欢，毛艳稳，任飞燕，王圆圆*，张帆，张莹莹，石明隽，肖瑛，桂华珍，汤磊，郭兵.吡格列酮改善糖尿病肾脏疾病肾小管间质纤维化病变的动物实验研究.中国糖尿病杂志, 2019, 27(1):56-61.

69.肖瑛，袁质平，彭灿，张小欢，张莹莹，王圆圆，石明隽，张帆，孙兰，郭兵*. α-硫辛酸抑制炎症信号TLR4和NLRP3的活化在糖尿病大鼠肾组织纤维化中的保护作用.中国药理学通报, 2019, 35(3):335-340.

70.张林山，王丽琨，任思颖，毛远红，李颖慧，伍国锋*.血肿形态特征对立体定向微创穿刺技术治疗脑出血预后的影响.中华老年心脑血管病杂志,2019,21(8):834-838.

71.孙达权*,王伟,周莉莉,刘恺烜,石松,薛殿婷,徐国强. Mmp2基因克隆及其对肝癌细胞的作用.基因组学与应用生物学,2019,38(7):3292-3296.

72.王琼,吴芳草,郭长城,刘芳,崔古贞,潘科,许良碧,张永宏,熊妍,印琳,吴晓娟,张峥嵘,陈峥宏*.以Real-time PCR方法检测耐药幽门螺杆菌中HefABC基因的表达.基因组学与应用生物学,2019(4):1797-1803.

73.文学琴,吴芳草,刘芳,朱键,胡越,雷静静,王彩霞,陈相好,崔古贞,王琼,印琳,陈峥宏*,谷俊莹*.幽门螺杆菌四环素耐药与16SrDNA突变的关系.中国病原生物学杂志,2019,14(4):433-438.

74.吴芳草,王琼,朱键,胡越,潘科,蒋强,雷静静,刘芳,文学琴,糜孟衡,王彩霞,崔古贞,陈峥宏*.贵阳地区351株幽门螺杆菌药物敏感性及pbp1多样性分析.中国人兽共患病学报,2019,35(7):587-593.

75.夏雪，许筱莉，龙金华，王赟，张世超，欧阳燕，朱贵明，胡祖权*，曾柱*.白介素10对人mDCs细胞骨架结构及其结合蛋白的影响.安徽医科大学学报,2019,54(12):1855-1859.

76.张毅,汤磊*.卡培他滨的合成工艺改进.化学研究与应用,2019,31(4):768-772.

77.杨果,李应贤,程铖,周顺,郑丹丹,杨元勇,汤磊*.单取代1,3-[2H,4H]-异喹啉二酮的合成.科学技术与工程,2019(9):10-14.

78.张吉泉,武婷婷,马才玉,马晓,王建塔,汤磊*. N-芳酰基取代的二氢吲哚-3-乙酸类衍生物的设计、合成与体外降糖活性研究.中国药房,2019,30(3):318-322.

79.樊玲玲,李毅,罗碧兰,范菊娣,李永,汤磊*.吡嗪类化合物的合成及其抗血小板凝集活性测试.化学通报,2019,82(2):128-132+97.

80.张吉泉,李述敏,武婷婷,彭金刚,马晓,段习琴,汤磊*.吲哚-3-羧酸类化合物的设计、合成及体外降糖活性研究.化学试剂,2019,41(1):18-22.

81.李述敏,武婷婷,王兴兰,张吉泉,汤磊*. Gedatolisib的合成.中国医药工业杂志,2019,50(1):59-62.

82.杨牧野，欧阳伟炜，苏胜发，马筑，李青松，耿一超，王羽，罗大先，杨文刚，胡银祥，栗蕙芹，何志旭，卢冰*.治疗后生存状态变化对Ⅳ期非小细胞肺癌化疗同期三维放射治疗生存的影响.中华放射医学与防护杂志,2019;39(1): 51-57.

83.罗兰，欧阳伟炜，苏胜发，马筑，李青松，杨文刚，付士美，卢冰*.原发肿瘤体积对IV期非小细胞肺癌生存影响--来自多中心II期前瞻性临床研究结果再分析.中华放射肿瘤学杂志,2019;28(9):660-664.

84.付卫旭，欧阳伟炜，苏胜发，马筑，李青松，耿一超，罗大先，杨文刚，胡银祥，栗蕙芹，何志旭，卢冰*.同期放化疗对不同年龄IV期非小细胞肺癌生存影响--两项前瞻性研究再分析.中华放射肿瘤学杂志,2019;28（4）:262-267.

85.孙达权*,石静,石松,薛殿婷,徐莹莹.桩蛋白基因克隆及其在肝癌细胞Hep G2中的作用.新医学,2019,50(9):671-675.

86.孙达权*,周莉莉,石松,薛殿婷,徐莹莹.细胞角蛋白18的基因克隆及其对Hep G2肝癌细胞增殖迁移的影响.遵义医学院学报,2019,42(4):383-387.

87.袁桃花，李欣芯，陈丽亚，曹胜宇，孙见飞，刘华，吴昌学*，吴宁*.苗药验方“四大血”对胶原诱导关节炎大鼠IL-17和VEGF表达的影响.贵州医科大学学报, 2019, 44(6): 664-669.

88.刘务玲，姚尧，陈娟，吴昌学，宋晶睿，王春林，邱剑飞，王立平，朱伟明，龙群*，李艳梅*.双吲哚马来酰亚胺衍生物GZWM-051对HEL细胞周期及分化的影响.贵州医科大学学报, 2019, 44(9): 993-998.

89.刘务玲，姚尧，陈娟，吴昌学，宋晶睿，王春林，邱剑飞，王立平，朱伟明，龙群*，李艳梅*. 双吲哚马来酰亚胺衍生物GZWM-051诱导白血病细胞凋亡的作用及机制.贵州医科大学学报, 2019, 44(6): 999-1004.

90.江银辉，杨碧，吴昌学，周建奖. PEG介导黄曲霉菌的遗传转化体系.贵州医科大学学报,2019,44(12):1390-1394.

91.卜苏洪，黄文湧，汪俊华，蒋芝月，官志忠，杨敬源* .贵州省两个少数民族地区乙肝感染家庭聚集性影响因素分析.贵州医科大学学报, 2019, 44(4): 447-452.

92.卜苏洪，黄文湧，汪俊华，蒋芝月，官志忠，杨敬源* .贵州省1115户居民家庭结构和乙肝感染家庭聚集性关系研究.贵州医科大学学报, 2019, 44(6): 658-663.

93.陈相好，蔡梦迪，陈峥宏，谷俊莹，文学琴，洪伟*，崔古贞* .艰难梭菌sigB基因簇CRISPR- Cas9敲除载体的构建及验证.贵州医科大学学报, 2019, 44(7): 751-756.

94.王婵娟，何燕，张婷，王治海，禹文峰，官志忠，安宇* .贵州地区非阻塞性无精症与SIRPA-SIRPG基因rs6080550多态性的相关性.贵州医科大学学报, 2019, 44(2): 169-172.

95.张秀秀，何燕*. Y染色体DNA遗传标记在汉藏语系民族研究中的应用.贵州医科大学学报, 2019, 44(4): 373-378.

96.张秀秀，喻艳琴，田薇，李鸣，王婵娟，张婷，单可人，朱卫芳，何燕* .贵州土家族16个Y-SNP多态性研究.贵州医科大学学报, 2019, 44(4): 379-385.

97.张秀秀，国学红，喻艳琴，朱卫芳，张婷，王婵娟，单可人，何燕*，吴昌学* . 22个Y-SNP在贵州满族人群的分布.贵州医科大学学报, 2019, 44(4): 386-392.

98.饶凤琴，吴昌学，崔古贞，程玉梅，齐晓岚*，洪伟* .艰难梭菌黏附因子研究进展.贵州医科大学学报, 2019, 44(10): 1117-1121.

99.饶凤琴，程玉梅，张婷，周青帅，崔古贞，齐晓岚*，洪伟* .艰难梭菌中粪肠球菌污染的去除方法.贵州医科大学学报, 2019, 44(10): 1122-1127.

100.饶凤琴，程玉梅，吴昌学，王义，崔古贞，齐晓岚*，洪伟* .敲除PaLoc毒力岛的无毒性艰难梭菌菌株的构建.贵州医科大学学报, 2019, 44(10): 1128-1133.

101.洪伟，赵行行，吴昌学，饶凤琴，程玉梅，张婷，齐晓岚，禹文峰，官志忠.人肠道来源大肠杆菌β-半乳糖苷酶基因突变株的构建.贵州医科大学学报, 2019, 44(12)

102.洪伟，饶凤琴，吴昌学，赵行行，程玉梅，张婷，齐晓岚，禹文峰，官志忠.人肠道来源艰难梭菌感染Caco-2细胞对NF-KB信号通路相关蛋白表达的影响.贵州医科大学学报, 2019, 44(12)

103.洪伟，钱声艳，吴昌学，饶凤琴，程玉梅，张婷，齐晓岚，禹文峰，官志忠.人肠道来源样品中肺炎克雷伯菌的分离及特征研究.贵州医科大学学报, 2019, 44(12)

104.王露娇子，左临轩，杨国强，李青，丁岭杰，赵亮.贵州少数民族地区农村三级医疗卫生服务网络现状调查.国外医学医学地理分册, 2019, 40(2): 113-117.

105.禹文峰，董智慧，任真奎，吴昌学* .热休克转录因子1及热休克蛋白70与阿尔茨海默病的关系.贵州医科大学学报, 2019, 44(3): 249-253.

106.董智慧，吕菊，任真奎，谢鹏，胡玉梅，官志忠，吴昌学*，禹文峰* . PNU通过PI3K/AKT信号通路上调星形胶质细胞HSP70的表达.贵州医科大学学报, 2019, 44(3): 254-258.

107.董智慧，任真奎，吕菊，谢鹏，官志忠，吴昌学*，禹文峰* .尼古丁通过PI3K/ AKT信号通路上调星形胶质细胞HSF1的表达.贵州医科大学学报, 2019, 44(3): 259-263.

108.刘雨霞，郑菊，肖子宇，张文萍，李毅，吴昌学，官志忠，肖雁* .外源性H2S对血管性痴呆大鼠海马MDA、SOD、Cyt C表达的影响.贵州医科大学学报, 2019, 44(4): 393-399.

109.刘雨霞，郑菊，张文萍，李毅，吴昌学，齐晓岚，官志忠，肖雁*.不同时间氧糖剥夺再灌注对SH-SY5Y细胞线粒体自噬及功能的影响.贵州医科大学学报, 2019, 44(4): 399-405.

110.向洁，曹坤，董阳婷，曾晓晓，徐毅，冉龙艳，邓婕，官志忠* .阿尔茨海默病患者不同脑区SOD-2与SIRT3的表达水平及相关性.贵州医科大学学报, 2019, 44(5): 497-502.

111.向洁，曾晓晓，曹坤，董阳婷，徐毅，冉龙艳，邓婕，官志忠* .氯化锂对APP /PS1双转基因小鼠脑组织中β淀粉样蛋白含量的影响.贵州医科大学学报, 2019, 44(5): 503-508.

112.李金河，葛章文，张望明，晏文涛，刘志*，吴昌学* .二氢杨梅素对肺癌A549细胞增殖和凋亡的影响.贵州医科大学学报, 2019, 44(10): 1140-1144.

113.杨健，李靖，彭潇，董莉，沈艳珍，李勇军，席晓岚*，刘亭*.骨康胶囊组方药物对成骨细胞SaOS-2增殖分化及矿化的影响.贵州医科大学学报,2019,44(2):158-162.

114.郑林，刘丽娜，李月婷，李勇军，黄勇，王永林，兰燕宇* .心脉通软胶囊的质量控制及稳定性考察.中国药业,2019,28(17):11-14.

115.刘春花，游景瑞，陈梅伦若，李勇军，曹闯，兰燕宇，刘亭*.毛叶和红叶木姜子果实性状特征及显微特征的鉴别.贵州医科大学学报,2019,44(9):1011-1015.

116.王圆圆,刘慧铭,梁露群,张会芳,向珈谊,郭兵*. HGF上调SnoN mRNA抑制高糖介导大鼠肾小管上皮细胞纤维病变机制.贵州医科大学学报,2019,44(10):1134-1139.

117.刘芳,王彩霞,綦廷娜,吴芳草,文学琴,陈峥宏*,崔古贞*.幽门螺杆菌菌落PCR的优化.贵州医科大学学报,2019,44(7):762-766.

118.刘芳,卢婷,蔡梦迪,吴芳草,陈相好,王彩霞,崔古贞,陈峥宏*. Cas9蛋白的克隆表达、分离纯化及多克隆抗体制备.贵州医科大学学报,2019,44(7):757-761+766.

119.王婵娟，何燕，张婷，单可人，禹文峰，官志忠，安宇* .贵州非阻塞性无精症与易感基因多态性的相关研究.重庆医学，2019,48(10): 1697-1704.

120.桂传枝，冉龙艳，官志忠.燃煤型氟中毒对大鼠脑组织NO含量及NOS mRNA和蛋白表达的影响.中国地方病防治杂志，2019,34(1):4-7.

121.胡晓红，柏华，段娟娟，雷秀，张启芳*.反馈激活STAT3调控HER2阳性乳腺癌细胞拉帕替尼耐药的机制.肿瘤防治研究, 2019, 46(4): 305-310.

122.洪伟，张婷，谢渊，沈祥春，康惠* .地方医学院校药学专业分子生物学实验课程改革与探索.中国当代医药, 2019, 26(30): 164-167.

123.刘亭，李靖，薛维娜*. PBL教学模式在生物技术制药理论课教学中的应用.科学大众(科学教育),2019(5):143-143+161.

124.刘亭，张煜彬，薛维娜*.基于PBL的生物技术制药实验教学改革.中国继续医学教育,2019,11(28):3-5.