郭兵

    郭兵，贵州省省管专家，国贴获得者，贵州省教学名师。中国病理生理学会理事，中国生理学会肾脏专业委员会委员，《中国病理生理杂志》编委。承担国家自然科学基金、国家科技部攻关及省级重点项目等30余项。获贵州省科技进步二等奖等奖项6项，发表科研论文140余篇，编写《病理生理学》教材三部。培养博士及硕士研究生60名。

       研究方向

       肾脏纤维化发病机制及药物防治研究

       代表性论文

       1. Yuanyuan Wang#, Xiaohuan Zhang#, Yanwen Mao, Luqun Liang, Lingling Liu, Wei Peng, Huiming Liu, Ying Xiao, Yingying Zhang, Fan Zhang, Mingjun Shi⁎, Lirong Liu*, Bing Guo⁎. Smad2 and Smad3 play antagonistic roles in high glucose-induced renal tubular fibrosis via the regulation of SnoN. Experimental and Molecular Pathology, 2020, 113:104375.

       2. Ying Xiao#, Can Peng#, Yawen Xiao, Dan Liang, Zhiping Yuan, Zhiyang Li, Mingjun Shi, Yuanyuan Wang, Fan Zhang and Bing Guo*. Oxymatrine Inhibits T wist-Mediated Renal Tubulointerstitial Fibrosis by Upregulating Id2 Expression. Frontiers in Physiology, 2020, 11: 559.

       3. Rui Yan, Yuanyuan Wang, Mingjun Shi, Ying Xiao, Lirong Liu, Lingling Liu, Bing Guo*. Regulation of PTEN/AKT/FAK pathways by PPARγ impacts on fibrosis in diabetic nephropathy. J Cell Biochem. 2019,120:6998-7014.

       4. Yingying Zhang#, Siqi Zhao#, Depei Wu, Xingmei Liu, Mingjun Shi, Yuanyuan Wang, Fan Zhang, Jing Ding, Ying Xiao* and Bing Guo*. MicroRNA-22 Promotes Renal Tubulointerstitial Fibrosis by Targeting PTEN and Suppressin g Autophagy in Diabetic Nephropathy. J Diabetes Res, 2018, Apr3,2018:4728645.

       5. Shan-Shan Rao, Xiang-Yan Zhang, Ming-Jun Shi, Ying Xiao, Ying-Ying Zhang, Yuan-Yuan Wang, Chang-Zhi Zhang, Song-Jun Shao, Xin-Mei Liu, Bing Guo*. Suberoylanilide hydroxamic acid attenuates paraquat-induced pulmonary fibrosis by preventing Smad7 from deacetylation in rats. Journal of Thoracic Disease. 2016,8(9):2485-2494.